Description:Rabbit polyclonal antibody to USP28Immunogen:KLH-conjugated synthetic peptide encompassing a sequence within the center region of human USP28. The exact sequence is proprietary.Purification:The antibody was purified by immunogen affinity chromatography.Clonality:PolyclonalForm:Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.Dilution:WB (1/500 - 1/1000), IH (1/50 - 1/100)Gene Symbol:USP28Alternative Names:KIAA1515; Ubiquitin carboxyl-terminal hydrolase 28; Deubiquitinating enzyme 28; Ubiquitin thioesterase 28; Ubiquitin-specific-processing protease 28
Entrez Gene (Human):
57646;
Entrez Gene (Mouse):
235323;
SwissProt (Human):
Q96RU2;
SwissProt (Mouse):
Q5I043;
Storage/Stability:Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of USP28 expression in HEK293T (A), A549 (B), mouse heart (C) whole cell lysates. (Predicted band size: 122 kD; Observed band size: 122 kD)
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Immunohistochemical analysis of USP28 staining in human prostate formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Stress granule-localized USP8 potentiates cGAS-mediated type I interferonopathies through deubiquitination of DDX3X