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CPA4071
  • Western blot analysis of MKK1/2 expression in HT29 (A), mouse brain (B) whole cell lysates. (Predicted band size: 43; 44 kD; Observed band size: 45 kD)
  • Immunohistochemical analysis of MKK1/2 staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Product Name:Anti-MKK1/2 Antibody
Cat No:CPA4071
Source:Rabbit
Reactivity:H, M, R, C, D, Mk, P, Rb
Applications:WB, IH
*Application Key:
H - Human, M - Mouse, R - Rat, B - Bovine, C - Chicken, D - Dog, G - Goat, Mk - Monkey, P - Pig, Rb - Rabbit, S - Sheep, Z - Zebrafish
*Species Reactivity Key:
E- ELISA, WB - Western blot, IH - Immunohistochemistry, IF - Immunofluorescence, FC - Flow cytometry, IC - Immunocytochemistry, IP - Immunoprecipitation, ChIP - Chromatin Immunoprecipitation, EMSA - Electrophoretic Mobility Shift Assay, BL - Blocking, SE - Sandwich ELISA, CBE - Cell-based ELISA, RNAi - RNA interference
Size
Price(USD)
200 μl
350
100 μl
220
30 μl
110
50 μl
150
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Description:Rabbit polyclonal antibody to MKK1/2
Immunogen:KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MKK1/2. The exact sequence is proprietary.
Purification:The antibody was purified by immunogen affinity chromatography.
Clonality:Polyclonal
Form:Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Dilution:WB (1/500 - 1/1000), IH (1/100 - 1/200)
Gene Symbol:MAP2K1; MAP2K2
Alternative Names:MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1; MAP2K2; MEK2; MKK2; PRKMK2; Dual specificity mitogen-activated protein kinase kinase 2; MAP kinase kinase 2; MAPKK 2; ERK activator kinase 2; MAPK/ERK kinase 2; MEK 2
Entrez Gene (Human): 5604; 5605;
Entrez Gene (Mouse): 26395; 26396;
Entrez Gene (Rat): 170851; 58960;
SwissProt (Human): Q02750; P36507;
SwissProt (Mouse): P31938; Q63932;
SwissProt (Rat): Q01986; P36506;
Storage/Stability:Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
  • Western blot analysis of MKK1/2 expression in HT29 (A), mouse brain (B) whole cell lysates. (Predicted band size: 43; 44 kD; Observed band size: 45 kD)
  • Immunohistochemical analysis of MKK1/2 staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
MicroRNA-1826 targets VEGFC, beta-catenin (CTNNB1) and MEK1 (MAP2K1) in human bladder cancer
Journal Carcinogenesis
IF 4.7
Application IHC-P
Reactivity Human
PMID 22049531
MicroRNA-1826 directly targets beta-catenin (CTNNB1) and MEK1 (MAP2K1) in VHL-inactivated renal cancer
Journal Carcinogenesis
IF 4.7
Application
Reactivity
PMID 22180573
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