Description:Rabbit polyclonal antibody to HSP70Immunogen:KLH-conjugated synthetic peptide encompassing a sequence within the center region of human HSP70. The exact sequence is proprietary.Purification:The antibody was purified by immunogen affinity chromatography.Clonality:PolyclonalForm:Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.Dilution:WB (1/500 - 1/1000), IH (1/100 - 1/200)Gene Symbol:HSPA1L; HSPA1AAlternative Names:HSPA1L; Heat shock 70 kDa protein 1-like; Heat shock 70 kDa protein 1L; Heat shock 70 kDa protein 1-Hom; HSP70-Hom; HSPA1A; HSPA1; HSPA1B; Heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1/2; HSP70-1/HSP70-2; HSP70.1/HSP70.2
Entrez Gene (Human):
3305;
3303;
3304;
Entrez Gene (Mouse):
15482;
193740;
Entrez Gene (Rat):
24963;
24472;
SwissProt (Human):
P34931;
P08107;
SwissProt (Mouse):
P16627;
Q61696;
SwissProt (Rat):
P55063;
Q07439;
Storage/Stability:Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of HSP70 expression in N2a (A), HEK293T (B), HepG2 (C), HCT116 (D), Jurkat (E), PC12 (F) whole cell lysates. (Predicted band size: 70 kD; Observed band size: 70 kD)
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Immunohistochemical analysis of HSP70 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
The E3 ubiquitin ligase STUB1 attenuates cell senescence by promoting the ubiquitination and degradation of the core circadian regulator BMAL1