Description:Rabbit polyclonal antibody to GNAT1Immunogen:KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GNAT1. The exact sequence is proprietary.Purification:The antibody was purified by immunogen affinity chromatography.Clonality:PolyclonalForm:Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.Dilution:WB (1/500 - 1/1000), IH (1/100 - 1/200)Gene Symbol:GNAT1Alternative Names:GNATR; Guanine nucleotide-binding protein G(t) subunit alpha-1; Transducin alpha-1 chain
Entrez Gene (Human):
2779;
Entrez Gene (Mouse):
14685;
SwissProt (Human):
P11488;
SwissProt (Mouse):
P20612;
Storage/Stability:Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
-
Western blot analysis of GNAT1 expression in mouse eyes (A), rat eyes (B) whole cell lysates. (Predicted band size: 40 kD; Observed band size: 40 kD)
-
Immunohistochemical analysis of GNAT1 staining in human heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Leukemia Inhibitory Factor (LIF) coordinates the downregulation of the visual cycle in the retina and retinal pigmented epithelium (RPE)