Description:Rabbit polyclonal antibody to BTK (Phospho-Y551)Immunogen:KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding Y551 of human BTK protein. The exact sequence is proprietary.Purification:The antibody was purified by immunogen affinity chromatography.Clonality:PolyclonalForm:Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.Dilution:WB (1/500 - 1/1000)Gene Symbol:BTKAlternative Names:AGMX1; ATK; BPK; Tyrosine-protein kinase BTK; Agammaglobulinemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; Bruton tyrosine kinase
Entrez Gene (Human):
695;
Entrez Gene (Mouse):
12229;
SwissProt (Human):
Q06187;
SwissProt (Mouse):
P35991;
Storage/Stability:Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of BTK (Phospho-Y551) expression in Jurkat (A), K562 (B) whole cell lysates. (Predicted band size: 76 kD; Observed band size: 75 kD)
Augmented TLR9-induced Btk activation in PIR-B-deficient B-1 cells provokes excessive autoantibody production and autoimmunity