Description:Rabbit polyclonal antibody to BRCC3Immunogen:Recombinant fusion protein of human BRCC3. The exact sequence is proprietary.Purification:The antibody was purified by immunogen affinity chromatography.Clonality:PolyclonalForm:Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.Dilution:WB (1/500 - 1/2000)Gene Symbol:BRCC3Alternative Names:BRCC36; C6.1A; CXorf53; Lys-63-specific deubiquitinase BRCC36; BRCA1-A complex subunit BRCC36; BRCA1/BRCA2-containing complex subunit 3; BRCA1/BRCA2-containing complex subunit 36; BRISC complex subunit BRCC36
Entrez Gene (Human):
79184;
Entrez Gene (Mouse):
210766;
Entrez Gene (Rat):
316794;
SwissProt (Human):
P46736;
SwissProt (Mouse):
P46737;
SwissProt (Rat):
B2RYM5;
Storage/Stability:Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
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Western blot analysis of BRCC3 expression in MCF7 (A), Jurkat (B), mouse brain (C), rat liver (D) whole cell lysates. (Predicted band size: 23; 28; 33; 36 kD; Observed band size: 33; 36 kD)
Lys‑63‑specific deubiquitinase BRCC37 enhances the sensitivity of multiple myeloma cells to lenalidomide by inhibiting lysosomal degradation of cereblon
Journal
Cellular and Molecular Life Sciences
IF
6.2
Application
WB, IF
Reactivity
Human
PMID
39136771